International Chemical Safety Cards

2-CHLORO-1-NITROBENZENE ICSC: 0028

2-CHLORO-1-NITROBENZENE
o-Chloronitrobenzene
o-Nitrochlorobenzene
1-Chloro-2-nitrobenzene
C6H4ClNO2
Molecular mass: 157.6
CAS # 88-73-3
RTECS # CZ0875000
ICSC # 0028
UN # 1578
TYPES OF
HAZARD/
EXPOSURE 		ACUTE HAZARDS/
SYMPTOMS 		PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Combustible. Many reactions may cause fire or explosion. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Powder, water spray, foam, carbon dioxide.
EXPLOSION Finely dispersed particles form explosive mixtures in air.
Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting.
In case of fire: keep drums, etc., cool by spraying with water.
 
EXPOSURE
PREVENT DISPERSION OF DUST! STRICT HYGIENE!

INHALATION Blue lips or finger nails. Blue skin. Dizziness. Headache. Nausea. Shortness of breath.
Local exhaust or breathing protection.
Fresh air, rest. Refer for medical attention.
SKIN MAY BE ABSORBED! Redness (further see Inhalation).
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
EYES Redness. Pain.
Safety goggles, or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
INGESTION (further see Inhalation).
Do not eat, drink, or smoke during work.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
Sweep spilled substance into sealable containers. Carefully collect remainder, then remove to safe place (extra personal protection: complete protective clothing including self-contained breathing apparatus).
Separated from food and feedstuffs, and reducing materials.
Do not transport with food and feedstuffs.
UN Hazard Class: 6.1
UN Packing Group: II
SEE IMPORTANT INFORMATION ON BACK
ICSC: 0028 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993

International Chemical Safety Cards

2-CHLORO-1-NITROBENZENE ICSC: 0028

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PHYSICAL STATE; APPEARANCE:
YELLOW TO GREEN CRYSTALS , WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:
Dust explosion possible if in powder or granular form, mixed with air.

CHEMICAL DANGERS:
The substance decomposes on heating or on burning producing toxic and corrosive fumes (nitrogen oxides, chlorine - see ICSC # 0126, hydrogen chloride, phosgene - see ICSC # 0007). Reacts violently with reducing materials, causing fire and explosion hazard.

OCCUPATIONAL EXPOSURE LIMITS (OELs):
TLV not established.
PDK: 1 mg/m3 P (USSR 19##)
(see Notes).


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation and through the skin.

INHALATION RISK:
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance irritates the eyes, the skin and the respiratory tract. The substance may cause effects on the blood , resulting in formation of methaemoglobin, cyanosis, brain damage and kidney failure (see Notes).

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The substance may have effects on the blood: methemoglobinemia (see short-term exposure), liver, kidney and spleen.
PHYSICAL
PROPERTIES
 Boiling point: 246°C
Melting point: 33°C
Relative density (water = 1): 1.3
Solubility in water: None
Vapour pressure, kPa at 20°C: 0.6		 Relative vapour density (air = 1): 5.4
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.03
Flash point: 124°C
Explosive limits, vol% in air: (see Notes)
Octanol/water partition coefficient as log Pow: 2.24
ENVIRONMENTAL
DATA
 This substance may be hazardous to the environment; special attention should be given to the water. In the food chain important to humans, bioaccumulation takes place, specifically in fish.
NOTES
TLV (as para-nitrochlorobenzene): 0.1 ppm; O.6 mg/m3 (skin) (ACGIH 1991-1992). Explosive limits are unknown in literature. Depending on the degree of exposure, periodic medical examination is indicated. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Transport Emergency Card: TEC (R)-877
NFPA Code: H3; F1; R1;
ADDITIONAL INFORMATION


ICSC: 0028 2-CHLORO-1-NITROBENZENE
© IPCS, CEC, 1993
IMPORTANT LEGAL NOTICE: Neither the CEC or the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use.