International Chemical Safety Cards CHLOROFORM ICSC: 0027 CHLOROFORM Trichloromethane Methane trichloride Formyl chloride CHCl3 Molecular mass: 119.4 CAS # 67-66-3 RTECS # FS9100000 ICSC # 0027 UN # 1888 EC # 602-006-00-4 TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Not combustible. See Notes. Gives off irritating or toxic fumes (or gases) in a fire. In case of fire in the surroundings: all extinguishing agents allowed. EXPLOSION Risk of fire and explosion (see Chemical Dangers). In case of fire: keep drums, etc., cool by spraying with water.   EXPOSURE STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN! INHALATION Cough. Drowsiness. Headache. Nausea. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Artificial respiration if indicated. Refer for medical attention. SKIN MAY BE ABSORBED! Redness. Pain. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention. EYES Redness. Pain. Face shield or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION Abdominal pain. Vomiting (further see Inhalation). Do not eat, drink, or smoke during work. Rinse mouth. Give plenty of water to drink. Rest. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Evacuate danger area! Consult an expert! Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT let this chemical enter the environment (extra personal protection: self-contained breathing apparatus). Separated from strong oxidants, strong bases, metals, acetone, food and feedstuffs. Keep in the dark. Ventilation along the floor. Unbreakable packaging; put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs. Xn symbol R: 22-38-40-48/20/22 S: 36/37 UN Hazard Class: 6.1 UN Packing Group: III Marine pollutant. SEE IMPORTANT INFORMATION ON BACK ICSC: 0027 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993

International Chemical Safety Cards CHLOROFORM ICSC: 0027 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: VOLATILE COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: The vapour is heavier than air. CHEMICAL DANGERS: On contact with hot surfaces or flames this substance decomposes forming irritating and toxic fumes (hydrogen chloride, ICSC # 0163; phosgene, ICSC # 0007; chlorine, ICSC # 0126). The substance decomposes slowly under influence of air and light. Reacts violently with strong bases, strong oxidants, some metals, such as aluminium, lithium, magnesium, potassium, sodium and acetone, causing fire and explosion hazard. Attacks plastic, rubber and coatings. OCCUPATIONAL EXPOSURE LIMITS (OELs): TLV (as TWA): 10 ppm; 50 mg/m3 (ACGIH 1992-1993). MAK: 10 ppm; 50 mg/m3; II,1, B (1992). MAK: class III B (1992). ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation, through the skin and by ingestion. INHALATION RISK: A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance irritates the eyes. The substance may cause effects on the heart, liver, kidneys and the central nervous system , resulting in unconsciousness. The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact with skin may cause dermatitis. This substance is possibly carcinogenic to humans. PHYSICAL PROPERTIES Boiling point: 62°C Melting point: -64°C Relative density (water = 1): 1.48 Solubility in water, g/100 ml at 20°C: 0.8 Vapour pressure, kPa at 20°C: 21.2 Relative vapour density (air = 1): 4.12 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.7 Octanol/water partition coefficient as log Pow: 1.97

ENVIRONMENTAL DATA	This substance may be hazardous to the environment; special attention should be given to water.
N O T E S
Turns combustible on addition of small amounts of a flammable substance or an increase in the oxygen content of the air. Use of alcoholic beverages enhances the harmful effect. Depending on the degree of exposure, periodic medical examination is indicated. The odour warning when the exposure limit value is exceeded is insufficient. Do NOT use in the vicinity of a fire or a hot surface, or during welding. Transport Emergency Card: TEC (R)-146 NFPA Code: H 2; F 0; R 0;

ADDITIONAL INFORMATION
ICSC: 0027 CHLOROFORM © IPCS, CEC, 1993

IMPORTANT LEGAL NOTICE: Neither the CEC or the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use.