International Chemical Safety Cards METHYL ISOCYANATE ICSC: 0004 METHYL ISOCYANATE Isocyanatomethane Isocyanic acid, methyl ester MIC CH3NCO Molecular mass: 57.1 CAS # 624-83-9 RTECS # NQ9450000 ICSC # 0004 UN # 2480 EC # 615-001-00-7 TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Highly flammable. Many reactions may cause fire or explosion. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames, NO sparks, and NO smoking. NO contact with water, acid(s), base(s), amines, alcohols, oxidizing agents. Alcohol-resistant foam, dry sand, powder, carbon dioxide. NO hydrous agents. EXPLOSION Vapour/air mixtures are explosive. Risk of fire and explosion when heated or in contact with water or catalysts. Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling. In case of fire: cool drums, etc., by spraying with water but avoid contact of the substance with water. Combat fire from a sheltered position.   EXPOSURE PREVENT GENERATION OF MISTS! AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR! INHALATION Corrosive. Cough. Dizziness. Laboured breathing. Shortness of breath. Sore throat. Unconsciousness. Vomiting. Local exhaust or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration if indicated. Refer for medical attention. SKIN Corrosive. MAY BE ABSORBED! Skin burns. Pain. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention. EYES Corrosive. Pain. Loss of vision. Severe deep burns. Face shield or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION Corrosive. Abdominal cramps. Sore throat. Vomiting. Do not eat, drink, or smoke during work. Rinse mouth. Do NOT induce vomiting. Give plenty of water to drink. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Evacuate danger area! Consult an expert! Ventilation. Collect leaking liquid in sealable containers. Absorb remaining liquid in dry sand or inert absorbent and remove to safe place. Do NOT wash away into sewer (extra personal protection: complete protective clothing including self-contained breathing apparatus). Fireproof. Separated from all other substances. Cool. Dry. Special material. F symbol T symbol R: 12-23/24/25-36/37/38 S: 9-30-43-44 UN Hazard Class: 6.1 UN Subsidiary Risks: 3 UN Packing Group: I SEE IMPORTANT INFORMATION ON BACK ICSC: 0004 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993

International Chemical Safety Cards METHYL ISOCYANATE ICSC: 0004 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: VOLATILE COLOURLESS LIQUID , WITH PUNGENT ODOUR. PHYSICAL DANGERS: The vapour is heavier than air and may travel along the ground; distant ignition possible. The vapour mixes well with air, explosive mixtures are easily formed. CHEMICAL DANGERS: The substance may polymerize due to heating or under the influence of water and catalysts. The substance decomposes on heating producing toxic gases (hydrogen cyanide, nitrogen oxides, carbon monoxide). Reacts with strong oxidants. Reacts violently with water, acids, alcohols, amines, iron, steel, zinc, tin, copper (or alloys of these metals) causing fire and explosion hazard. Attacks some forms of plastic, rubber and coatings. OCCUPATIONAL EXPOSURE LIMITS (OELs): TLV (as TWA): 0.02 ppm; 0.047 mg/m3 (skin) (ACGIH 1991-1992). PDK: 0.05 mg/m3 (USSR 1987). ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation, through the skin and by ingestion. INHALATION RISK: A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance is corrosive to the eyes, the skin and the respiratory tract. Inhalation of the vapour may cause lung oedema (see Notes). Exposure may result in death. The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the lungs , resulting in tissue lesions. PHYSICAL PROPERTIES Boiling point: 39°C Melting point: -45°C Relative density (water = 1): 0.96 Solubility in water: reaction Vapour pressure, kPa at 20°C: 46.4 Relative vapour density (air = 1): 1.97 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.4 Flash point: -7°C c.c. Auto-ignition temperature: 535°C Explosive limits, vol% in air: 5.3-26

ENVIRONMENTAL DATA	It is strongly advised not to let the chemical enter into the environment because of its toxicity to mammals.
N O T E S
Reacts violently with fire extinguishing agents such as water and/or hydrated agents. Depending on the degree of exposure, periodic medical examination is indicated. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. The odour warning when the exposure limit value is exceeded is insufficient. Do NOT take working clothes home. Transport Emergency Card: TEC (R)-624 NFPA Code: H2; F3; R3

ADDITIONAL INFORMATION
ICSC: 0004 METHYL ISOCYANATE © IPCS, CEC, 1993

IMPORTANT LEGAL NOTICE: Neither the CEC or the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use.