International Chemical Safety Cards 2-CHLOROACETOPHENONE ICSC: 0128 2-CHLOROACETOPHENONE 2-Chloro-1-phenylethanone a-Chloroacetophenone Phenacyl chloride C8H7ClO/C6H5COCH2Cl Molecular mass: 154.6 CAS # 532-27-4 RTECS # AM6300000 ICSC # 0128 UN # 1697 TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Powder, water spray, foam, carbon dioxide. EXPLOSION In case of fire: keep drums, etc., cool by spraying with water.   EXPOSURE STRICT HYGIENE! INHALATION Burning sensation. Cough. Nausea. Shortness of breath. Local exhaust or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration if indicated. Refer for medical attention. SKIN Redness. Pain. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention. EYES Redness. Pain. Blurred vision. Permanent partial loss of vision. Face shield or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Give plenty of water to drink. Rest. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into plastic sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place (extra personal protection: self-contained breathing apparatus). Separated from food and feedstuffs. Dry. Keep in a well-ventilated room. Do not transport with food and feedstuffs. UN Hazard Class: 6.1 UN Packing Group: II SEE IMPORTANT INFORMATION ON BACK ICSC: 0128 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993

International Chemical Safety Cards 2-CHLOROACETOPHENONE ICSC: 0128 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS TO GREY CRYSTALS. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating and on burning producing toxic and corrosive fumes including hydrogen chloride. OCCUPATIONAL EXPOSURE LIMITS (OELs): TLV: 0.05 ppm; 0.32 mg/m3 (ACGIH 1993-1994). ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation. INHALATION RISK: A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: Tear drawing. The substance irritates the eyes, the skin and the respiratory tract. Inhalation of vapour or aerosol may cause lung oedema (see Notes). The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization. PHYSICAL PROPERTIES Boiling point: 244-245°C Melting point: 54-59°C Relative density (water = 1): 1.3 Solubility in water: none Vapour pressure, Pa at 20°C: 0.7 Relative vapour density (air = 1): 5.3 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.0 Flash point: 118°C c.c. Octanol/water partition coefficient as log Pow: 2.08

ENVIRONMENTAL DATA
N O T E S
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. The odour warning when the exposure limit value is exceeded is insufficient. Chemical Mace, CAP, CN are trade names. Transport Emergency Card: TEC (R)-61G12b NFPA Code: H 2; F 1; R 0;

ADDITIONAL INFORMATION
ICSC: 0128 2-CHLOROACETOPHENONE © IPCS, CEC, 1993

IMPORTANT LEGAL NOTICE: Neither the CEC or the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use.