International Chemical Safety Cards ISOPHORONE DIISOCYANATE ICSC: 0499 ISOPHORONE DIISOCYANATE 3-Isocyanatomethyl-3,5,5-trimethylcyclohexylisocyanate IPDI C12H18N2O2 Molecular mass: 222.32 CAS # 4098-71-9 RTECS # NQ9370000 ICSC # 0499 UN # 2290 EC # 615-008-00-5 TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. NO open flames. Water spray, powder. EXPLOSION In case of fire: keep drums, etc., cool by spraying with water.   EXPOSURE PREVENT GENERATION OF MISTS! AVOID ALL CONTACT! INHALATION Cough. Sore throat. Symptoms may be delayed (see Notes). Ventilation. Fresh air, rest. Artificial respiration if indicated. Refer for medical attention. SKIN Redness. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention. Wear protective gloves when administering first aid. EYES Redness. Safety goggles or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION Do NOT induce vomiting. Rest. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Evacuate danger area! Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer (extra personal protection: complete protective clothing including self-contained breathing apparatus). Fireproof. Separated from strong oxidants, food and feedstuffs. Cool. Dry. Airtight. Do not transport with food and feedstuffs. T symbol R: 23-36/37/38-42/43 S: 26-28-38-45 UN Hazard Class: 6.1 UN Packing Group: III SEE IMPORTANT INFORMATION ON BACK ICSC: 0499 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993

International Chemical Safety Cards ISOPHORONE DIISOCYANATE ICSC: 0499 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS TO YELLOW LIQUID , WITH PUNGENT ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating producing toxic fumes (nitrogen oxides). Reacts with oxidants, acids, alcohols, amines, amides, mercaptanes. Attacks many metals, plastics, and rubber. OCCUPATIONAL EXPOSURE LIMITS (OELs): TLV: 0.005 ppm; 0.045 mg/m3 (skin) (ACGIH 1991-1992). ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. INHALATION RISK: A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance irritates the eyes, the skin and the respiratory tract. Inhalation of aerosol may cause asthmatic reactions (see Notes). EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact may cause skin sensitization. Lungs may be affected by repeated or prolonged exposure (sensitization). PHYSICAL PROPERTIES Boiling point at 13.3 kPa: 216°C Melting point: -60°C Relative density (water = 1): 1.06 Solubility in water: reacts Vapour pressure, Pa at 20°C: 0.04 Flash point: 155-161°C Auto-ignition temperature: 430°C

ENVIRONMENTAL DATA
NOTES
Explosive limits are unknown in literature. The applying occupational exposure limit value should not be exceeded during any part of the working exposure. The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Anyone who has shown symptoms of asthma due to this substance should never again come into contact with this substance. The odour warning when the exposure limit value is exceeded is insufficient. Transport Emergency Card: TEC (R)-645 NFPA Code: H 3; F 1; R 2; no water

ADDITIONAL INFORMATION
ICSC: 0499 ISOPHORONE DIISOCYANATE © IPCS, CEC, 1993

IMPORTANT LEGAL NOTICE: Neither the CEC or the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use.