International Chemical Safety Cards MALATHION ICSC: 0172 MALATHION S-1,2-bis(Ethoxycarbonyl)ethyl O,O-dimethylphosphorodithioate Butanedioic acid, {(dimethoxyphosphinothioyl)thio}-, diethyl ester C10H19O6PS2 Molecular mass: 330.4 CAS # 121-75-5 RTECS # WM8400000 ICSC # 0172 UN # 3082 EC # 015-041-00-X TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Powder, AFFF, foam, carbon dioxide. EXPLOSION Risk of fire and explosion if formulations contain flammable/explosive solvents.   EXPOSURE PREVENT GENERATION OF MISTS! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN! IN ALL CASES CONSULT A DOCTOR! INHALATION Dizziness. Pupillary constriction. Muscle cramp. Excessive salivation. Sweating. Laboured breathing. Unconsciousness. Symptoms may be delayed (see Notes). Ventilation, local exhaust, or breathing protection. Fresh air, rest. Half-upright position. Refer for medical attention. SKIN (Further see Inhalation). Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention. EYES Safety spectacles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION Abdominal cramps. Diarrhoea. Nausea. Vomiting (further see Inhalation). Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Rest. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer (extra personal protection: A/P2 filter respirator for organic vapour and harmful dust). Provision to contain effluent from fire extinguishing. Separated from strong oxidants, food and feedstuffs. Keep in a well-ventilated room. Do not transport with food and feedstuffs. Xn symbol R: 22 S: (2-)24 UN Hazard Class: 9 UN Packing Group: III Marine pollutant. SEE IMPORTANT INFORMATION ON BACK ICSC: 0172 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993

International Chemical Safety Cards MALATHION ICSC: 0172 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: CLEAR, YELLOW TO DEEP BROWN (DEPENDING ON THE PURITY) LIQUID , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating or on burning producing toxic fumes including phosphorous oxides and sulfur oxides. Reacts violently with strong oxidants. Attacks iron and some other metals, some plastics and rubber. OCCUPATIONAL EXPOSURE LIMITS (OELs): TLV: ppm; 10 mg/m3 (skin) (ACGIH 1994). ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation, through the skin and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying. EFFECTS OF SHORT-TERM EXPOSURE: The substance may cause effects on the nervous system , resulting in convulsions, respiratory failure. Cholinesterase inhibitor. Exposure above OEL may result in death. The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact may cause skin sensitization. Cholinesterase inhibitor; cumulative effect is possible: see acute hazards/symptoms. PHYSICAL PROPERTIES Boiling point at 0.093 kPa: 156-157°C Melting point: 3°C Relative density (water = 1): 1.2 Solubility in water: none Vapour pressure, Pa at 30°C: 0.0053 Relative vapour density (air = 1): 11.4 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00 Octanol/water partition coefficient as log Pow: 2.89

ENVIRONMENTAL DATA	The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment; special attention should be given to honey bees. Avoid release to the environment in circumstances different to normal use.
N O T E S
Depending on the degree of exposure, periodic medical examination is indicated. The symptoms of acute intoxication do not become manifest until before 30 minutes or 1-2 hours. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s). Carrier solvents used in commercial formulations may change physical and toxicological properties. Carbofos, Celthion, Cythion, Emmatos, Fosfothion, Fyfanon, Karbofos, Kypfos, Malamar, Malatol, Malatox, Sadophos, Sumitox, Zithiol are trade names.

ADDITIONAL INFORMATION
ICSC: 0172 MALATHION © IPCS, CEC, 1993

IMPORTANT LEGAL NOTICE: Neither the CEC or the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use.