International Chemical Safety Cards METHAMIDOPHOS ICSC: 0176 METHAMIDOPHOS O,S-Dimethyl phosphoramidothioate Phosphoramidothioic acid, O,S-dimethyl ester C2H8NO2PS Molecular mass: 141.1 CAS # 10265-92-6 RTECS # TB4970000 ICSC # 0176 UN # 2783 EC # 015-095-00-4 TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible under specific conditions. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Powder, alcohol-resistant foam, water spray, carbon dioxide. EXPLOSION Risk of fire and explosion if formulations contain flammable/explosive solvents.   EXPOSURE PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN! INHALATION Dizziness. Sweating. Laboured breathing. Unconsciousness. Weakness. Pupillary constriction, muscle cramp, excessive salivation (see Ingestion). Ventilation (not if powder), local exhaust, or breathing protection. Fresh air, rest. Half-upright position. Refer for medical attention. See Notes. SKIN MAY BE ABSORBED! (Further see Inhalation). Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention (See Notes). EYES Redness. Pain. Blurred vision. Face shield or eye protection in combination with breathing protection if powder. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION Abdominal cramps. Convulsions. Diarrhoea. Nausea. Vomiting. Muscle twitching (further see Inhalation). Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Give a slurry of activated charcoal in water to drink. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Rest. Refer for medical attention. See Notes. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Do NOT wash away into sewer. Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place (extra personal protection: complete protective clothing including self-contained breathing apparatus). Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Dry. Keep in a well-ventilated room. Unbreakable packaging; put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs. T+ symbol R: 24-28-36 S: (1/2-)22-28-36/37-45 UN Hazard Class: 6.1 UN Packing Group: II Marine pollutant. SEE IMPORTANT INFORMATION ON BACK ICSC: 0176 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993

International Chemical Safety Cards METHAMIDOPHOS ICSC: 0176 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS CRYSTALS. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating and on burning producing toxic and irritating fumes including nitrogen oxides, sulfur oxides, and phosphorous oxides. Attacks mild steel and copper-containing alloys (technical grade). OCCUPATIONAL EXPOSURE LIMITS (OELs): TLV not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation, through the skin and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered. EFFECTS OF SHORT-TERM EXPOSURE: The substance irritates the eyes. The substance may cause effects on the central nervous system , resulting in convulsions, respiratory failure. Cholinesterase inhibitor. Exposure may result in death. The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the nervous system , resulting in delayed neuropathy. Cholinesterase inhibitor; cumulative effect is possible: see acute hazards/symptoms. PHYSICAL PROPERTIES Melting point: 44°C Relative density (water = 1): 1.3 Solubility in water: good Vapour pressure, Pa at 20°C: 0.002 Octanol/water partition coefficient as log Pow: -0.66

ENVIRONMENTAL DATA	This substance may be hazardous to the environment; special attention should be given to birds, honey bees and fish.
N O T E S
Use of alcoholic beverages enhances the harmful effect. Depending on the degree of exposure, periodic medical examination is indicated. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s). Carrier solvents used in commercial formulations may change physical and toxicological properties. Do NOT take working clothes home. Bay 71628, Monitor, Pillaron, SRA 5172 and Tamaron are trade names. If the substance is present under the form of a formulation containing hydrocarbon solvents, vomiting may not be induced. Transport Emergency Card: TEC (R)-61G41b

ADDITIONAL INFORMATION
ICSC: 0176 METHAMIDOPHOS © IPCS, CEC, 1993

IMPORTANT LEGAL NOTICE: Neither the CEC or the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use.