International Chemical Safety Cards PIPERIDINE ICSC: 0317 PIPERIDINE Hexahydropyridine Azacyclohexane Pentamethyleneimine CH2(CH2)4NH Molecular mass: 85.2 CAS # 110-89-4 RTECS # TM3500000 ICSC # 0317 UN # 2401 EC # 613-027-00-3 TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Highly flammable. NO open flames, NO sparks, and NO smoking. Powder, alcohol-resistant foam, water spray, carbon dioxide. Fire fighters should wear complete protective clothing including self-contained breathing apparatus. EXPLOSION Vapour/air mixtures are explosive. Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling. In case of fire: keep drums, etc., cool by spraying with water.   EXPOSURE AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR! INHALATION Corrosive. Burning sensation. Cough. Laboured breathing. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration if indicated. Refer for medical attention. SKIN Corrosive. MAY BE ABSORBED! Redness. Skin burns. Pain. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention. EYES Corrosive. Redness. Pain. Blurred vision. Severe deep burns. Safety goggles, face shield, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION Corrosive. Abdominal pain. Laboured breathing. Nausea. Vomiting. Collapse. Salivation. Do not eat, drink, or smoke during work. Rinse mouth. Do NOT induce vomiting. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place (extra personal protection: self-contained breathing apparatus). Fireproof. Separated from strong oxidants, acids. F symbol T symbol R: 11-23/24-34 S: 16-26-27-44 UN Haz Class: 3 UN Pack Group: II SEE IMPORTANT INFORMATION ON BACK ICSC: 0317 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities © IPCS CEC 1993

International Chemical Safety Cards PIPERIDINE ICSC: 0317 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: The vapour is heavier than air and may travel along the ground; distant ignition possible. CHEMICAL DANGERS: The substance decomposes on heating and on burning producing toxic gases such as nitrogen oxides. The substance is a medium strong base. Reacts violently with oxidants. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation and through the skin and by ingestion. INHALATION RISK: No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance is corrosive to the eyes, the skin and the respiratory tract. Corrosive on ingestion. Inhalation of the vapour may cause lung oedema (see Notes). Exposure could cause blood pressure increase. The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: PHYSICAL PROPERTIES Boiling point: 106°C Melting point: -7°C Relative density (water = 1): 0.86 Solubility in water: miscible Vapour pressure, kPa at 29.2°C: 5.3 Relative vapour density (air = 1): 3.0 Flash point: 16°C Octanol/water partition coefficient as log Pow: 0.84

ENVIRONMENTAL DATA
NOTES
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Immediate administration of an appropriate spray, by a doctor or a person authorized by him/her, should be considered. Transport Emergency Card: TEC (R)-30G31 NFPA Code: H 2; F 3; R 3;

ADDITIONAL INFORMATION
ICSC: 0317 PIPERIDINE © IPCS, CEC, 1993

IMPORTANT LEGAL NOTICE: Neither the CEC or the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use.